# The Great Oxygenation - The diverity of [[bacteria]] exploded during the [[Archaean]], leading to the evolution of [[Cyanobacteria]] - This does not mean that [[Spirulina]] existed during the [[Archaean]]: it is a modern organism - There was almost no O₂ in the atmosphere before the [[Archaean]]-[[Proterozoic]] break - No O₂ means no formation of peroxides - Peroxides are dangerous to many cells as they rob electrons from proteins, fatally altering them - Cells had to develop anti-oxidation defenses, including [[catalase]] - Cells had two ways to adapt to O₂ 1. Become a strict anaerobe, and avoid oxygen-containing habitats 2. Tolerate O₂ - O₂ toleration can easily lead to aerobic metabolism